지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.5
- 수록면
- 31 - 38 (8page)
이용수
초록· 키워드
오류제보하기
Background: Avian pathogenic Escherichia coli (APEC) causes colibacillosis, resulting in significant economic losses in the poultry industry.Objectives: In this study, the molecular characteristics of two extended-spectrum betalactamase (ESBL)-producing APEC isolates were compared with previously reported ESBLproducing E. coli isolates.
Methods: The molecular characteristics of E. coli isolates and the genetic environments of the ESBL genes were investigated using whole genome sequencing.
Results: The two ESBL-producing APEC were classified into the phylogenetic groups C and B1 and ST410 and ST162, respectively. Moreover, the ESBL genes of the two isolates were harbored in different Inc plasmids. The EC1809182 strain, harboring the blaCTX-M-55 gene on the plasmid, exhibited extensive homology to IncFIB (98.4%) and IncFIC(FII) (95.8%). The EC1809191 strain, harboring the blaCTX-M-1 gene, was homologous to IncI1-I (Gamma) (99.3%). All chromosomes carried the multidrug transporter, mdf(A) gene. Mobile genetic elements, adjacent to CTX-M genes, facilitated the dissemination of genes in the two isolates, analogous to other ESBL-producing E. coli isolates.
Conclusions: This study clarifies the transmission dynamics of CTX-M genes and supports strengthened surveillance to prevent the transmission of the antimicrobial-resistant genes to humans via the food chain.
Methods: The molecular characteristics of E. coli isolates and the genetic environments of the ESBL genes were investigated using whole genome sequencing.
Results: The two ESBL-producing APEC were classified into the phylogenetic groups C and B1 and ST410 and ST162, respectively. Moreover, the ESBL genes of the two isolates were harbored in different Inc plasmids. The EC1809182 strain, harboring the blaCTX-M-55 gene on the plasmid, exhibited extensive homology to IncFIB (98.4%) and IncFIC(FII) (95.8%). The EC1809191 strain, harboring the blaCTX-M-1 gene, was homologous to IncI1-I (Gamma) (99.3%). All chromosomes carried the multidrug transporter, mdf(A) gene. Mobile genetic elements, adjacent to CTX-M genes, facilitated the dissemination of genes in the two isolates, analogous to other ESBL-producing E. coli isolates.
Conclusions: This study clarifies the transmission dynamics of CTX-M genes and supports strengthened surveillance to prevent the transmission of the antimicrobial-resistant genes to humans via the food chain.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Beta-amyloid imaging in dementia
영남의대학술지
2018 .01
-
반려동물에서 분리된 cefotaxime 내성 그람 음성균에서 CTX-M β-lactamase와 plasmid 매개 퀴놀론 내성 유전자
한국가축위생학회지
2020 .01
-
Occurrence of CTX-M-producing Escherichia coli from in broilers with colibacillosis
예방수의학회지
2022 .09
-
CTX-M 광범위 베타락탐 분해효소의 그룹별 내성표현형 차이
Annals of Clinical Microbiology
2019 .01
-
CTx might Take Over RT
대한외과학회 학술대회 초록집
2018 .11
-
Beta-Lactam Plus Macrolide for Patients Hospitalized With Community-Acquired Pneumonia: Difference Between Autumn and Spring
Journal of Korean Medical Science
2022 .11
-
Clavulanic Acid Is a Leading Culprit Beta-Lactam in Immediate Allergic Reactions to Penicillins
Allergy, Asthma & Immunology Research
2023 .03
-
Clinical Outcomes of Non-carbapenem Treatment for Urinary Tract Infections Caused by Extended-spectrum β-lactamase-producing Escherichia coli
Childhood Kidney Diseases
2021 .01
-
자돈 분변 유래 병원성 대장균의 병원성 인자 및 항생제 내성 양상
한국가축위생학회지
2023 .03
-
간경변 환자에서 발생한 Extended-spectrum Beta-lactamase 생성 Eshcerichia coli에 의한 지역발생 괴사성 근막염 1예
대한내과학회지
2017 .01
-
Profiling of antimicrobial resistance and plasmid replicon types in β-lactamase producing Escherichia coli isolated from Korean beef cattle
Journal of Veterinary Science
2015 .12
-
Thymosin Beta-4, Actin-Sequestering Protein Regulates Vascular Endothelial Growth Factor Expression via Hypoxia-Inducible Nitric Oxide Production in HeLa Cervical Cancer Cells
Biomolecules & Therapeutics(구 응용약물학회지)
2015 .01
-
β-Adrenergic Receptor and Insulin Resistance in the Heart
Biomolecules & Therapeutics(구 응용약물학회지)
2017 .01
-
Management of Extended-Spectrum Beta-Lactamase-Positive Gram-Negative Bacterial Urologic Infections
Urogenital Tract Infection
2015 .01
-
Clinical Impact of Beta Blockers in Patients with Myocardial Infarction from the Korean National Health Insurance Database
Korean Circulation Journal
2020 .01
-
Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors
Biomolecules & Therapeutics(구 응용약물학회지)
2017 .01
-
알코올 의존 환자군의 뇌파 특성 : 3차원적 신호원 국소화
생물정신의학
2015 .01
-
아밀로이드 베타로 유발한 알츠하이머병 모델에서 신선초의 기억력 개선 효과
대한본초학회지(본초분과학회지)
2019 .01
-
High Prevalence of AmpC β-Lactamases in Clinical Isolates of Escherichia coli in Ilam, Iran
Osong Public Health and Research Persptectives
2015 .01
-
Epidemiology and Characteristics of Metallo-β-Lactamase-Producing Pseudomonas aeruginosa
Infection and Chemotherapy
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2023-528-001317167